Tracking Bacterial Riboregulation by DsrA Noncoding RNA
نویسندگان
چکیده
منابع مشابه
Riboregulation of the bacterial actin-homolog MreB by DsrA small noncoding RNA.
The bacterial actin-homolog MreB is a key player in bacterial cell-wall biosynthesis and is required for the maintenance of the rod-like morphology of Escherichia coli. However, how MreB cellular levels are adjusted to growth conditions is poorly understood. Here, we show that DsrA, an E. coli small noncoding RNA (sRNA), is involved in the post-transcriptional regulation of mreB. DsrA is requir...
متن کاملSUPPLEMENTARY TEXT Positive Regulatory Dynamics by DsrA noncoding RNA
1 Department of Condensed Matter Physics, Facultad de Ciencias, Universidad Autónoma de Madrid, Madrid, Spain, and Instituto ’Nicolás Cabrera’, Facultad de Ciencias, Universidad Autónoma de Madrid, 28049 Madrid, Spain 2 Laboratoire Léon Brillouin, Commissariat lEnergie Atomique, CNRS-UMR 12, CEA-Saclay, Gif-surYvette Cedex F-91191 3 Laboratoire Jean Perrin, FRE 3132 CNRS-Paris 6 Paris F-75006 4...
متن کاملRiboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple loci.
DsrA is an 87-nt untranslated RNA that regulates both the global transcriptional silencer and nucleoid protein H-NS and the stationary phase and stress response sigma factor RpoS (sigmas). We demonstrate that DsrA acts via specific RNA:RNA base pairing interactions at the hns locus to antagonize H-NS translation. We also give evidence that supports a role for RNA:RNA interactions at the rpoS lo...
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DsrA is an Escherichia coli small noncoding RNA that acts by base pairing to some mRNAs in order to control their translation and turnover. It was recently shown that DsrA is able to self-associate in a way similar to DNA and to build nanostructures. Although functional consequence of this RNA self-assembly in vivo is not yet understood, the formation of such an assemblage more than likely infl...
متن کاملThe small noncoding DsrA RNA is an acid resistance regulator in Escherichia coli.
DsrA RNA is a small (87-nucleotide) regulatory RNA of Escherichia coli that acts by RNA-RNA interactions to control translation and turnover of specific mRNAs. Two targets of DsrA regulation are RpoS, the stationary-phase and stress response sigma factor (sigmas), and H-NS, a histone-like nucleoid protein and global transcription repressor. Genes regulated globally by RpoS and H-NS include stre...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2012
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2011.11.3514